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Hyperparathyroidism-jaw tumour (HPT-JT) syndrome is a rare autosomal dominant cause of familial hyperparathyroidism associated with ossifying fibromas (OF) of the maxillofacial bones and increased risk of parathyroid carcinoma, caused by inactivating germline mutation of the cell division cycle 73 (CDC73) gene.

acta endocrinologica (bucharest)

High Risk of Parathyroid Carcinoma and Genetic Screening in the First Diagnosed Romanian Family with Hyperparathyroidism-Jaw Tumor Syndrome and a Germline Mutation of the CDC73 Gene