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To compare two chromatographic methodologies for determination of plasma phenylalanine (Phe) and their usefulness for diagnosing hyperphenylalaninemia (HPA) and phenylketonuria (PKU).

acta endocrinologica (bucharest)

Comparison of Plasma Phenylalanine Determination by Densitometry of Thin-Layer Chromatograms and by High Performance Liquid Chromatography in Relation with the Screening of Phenylketonuria