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Autoimmune thyroid disease is considered a multifactorial disorder in which autoimmunity against thyroid antigens is facilitated by exposure to endogenous and environmental factors. We present here a rare case of identical female twins who developed consecutively Graves' disease within a few months and had three HLA susceptibility alleles for the development of Graves' disease.

Identical Twin Sisters with Close Onset of Graves’ Disease and with Multiple HLA Susceptibility Alleles for Graves’ Disease