Open AccessMucus Plugs and Small Airway Dysfunction in Asthma, COPD, and Asthma-COPD Overlap
Author(s) -
Kanami Tamura,
Toshihiro Shirai,
Keita Hirai,
Hiromasa Nakayasu,
Shigekazu Takahashi,
Yutaro Kishimoto,
Taisuke Akamatsu,
Kazuhiro Asada,
Satoshi Kato
Publication year - 2022
Publication title -
allergy, asthma and immunology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 45
eISSN - 2092-7363
pISSN - 2092-7355
DOI - 10.4168/aair.2022.14.2.196
Subject(s) - copd , medicine , spirometry , asthma , mucus , airway , exhaled nitric oxide , respiratory system , airway obstruction , anesthesia , biology , ecology
There are reports concerning mucus plugs detected on high-resolution computed tomography images and airflow obstruction in asthma and chronic obstructive pulmonary disease (COPD). However, little is known about the associations between mucus plugs and small airway dysfunction (SAD). We evaluated the relationship between mucus plugs and pulmonary function in patients with asthma, COPD, and asthma-COPD overlap (ACO), and investigated the relevance to SAD and type 2 inflammation in a retrospective study.