Open AccessThe Role ofIn VitroDetection of Drug-Specific Mediator-Releasing Cells to Diagnose Different Phenotypes of Severe Cutaneous Adverse Reactions
Author(s) -
Jettag Klaewsongkram,
Supranee Buranapraditkun,
Pattarawat Thantiworasit,
Pawinee Rerknimitr,
Papapit Tuchinda,
Leena Chularojanamontri,
Ticha Rerkpattanapipat,
Kumutnart Chanprapaph,
Wareeporn Disphanurat,
Panlop Chakkavittumrong,
Napatra Tovanabutra,
Chutika Srisuttiyakorn,
Yuttana Srinoulprasert,
Chonlaphat Sukasem,
Yuda Chongpison
Publication year - 2021
Publication title -
allergy, asthma and immunology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 45
eISSN - 2092-7363
pISSN - 2092-7355
DOI - 10.4168/aair.2021.13.6.896
Subject(s) - elispot , culprit , medicine , drug , peripheral blood mononuclear cell , granzyme b , immunology , toxic epidermal necrolysis , pharmacology , in vitro , immune system , dermatology , biology , t cell , biochemistry , myocardial infarction
The purpose of this study was to investigate panels of enzyme-linked immunospot assays (ELISpot) to detect drug-specific mediator releasing cells for confirming culprit drugs in severe cutaneous adverse reactions (SCARs).