Open AccessMucinous tubular and spindle cell carcinoma: A difficult diagnosis
Author(s) -
Juhi Bharti,
Gautam Ram Choudhary,
Vijay Kumar Sarma Madduri,
Taruna Yadav
Publication year - 2021
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/ua.ua_44_20
Subject(s) - medicine , histopathology , papillary renal cell carcinomas , malignancy , pathology , renal cell carcinoma , immunophenotyping , stage (stratigraphy) , clear cell , immunology , flow cytometry , biology , paleontology
Mucinous Tubular and Spindle Cell Carcinoma (MTSCC) is infrequently seen renal malignancy with favorable outcome, when diagnosed in the early stage. Once out of kidney it is have lethal course. Radiologically MTSCC is heterogeneously hypo-enhancing renal mass in delayed phase, may mimic to papillary renal cell carcinoma and in histopathology showed these tumoral cells shows complex immunophenotype expression. As this does not show enhancement pattern of common renal cell carcinomas, radiological diagnosis may be challenging. Histopathological reporting is also tedious indeed necessary to reach definitive diagnosis, which help in tailoring follow up and prognosis. Metastatic disease has dismal outcome and responds poorly with adjuvant therapy and patient succumbs within short span of time.