Open AccessEffect of preoperative finasteride on perioperative blood loss during transurethral resection of the prostate and on microvessel density in patients with benign prostatic hyperplasia: An open label randomized controlled trial
Author(s) -
Uma Kant Dutt,
Sunil Kumar,
Lalgudi Narayanan Dorairajan,
Bhawana Ashok Badhe,
Ramanitharan Manikandan,
S. K. Singh
Publication year - 2021
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/ua.ua_35_20
Subject(s) - medicine , finasteride , urology , prostate , transurethral resection of the prostate , perioperative , hyperplasia , placebo , surgery , cancer , pathology , alternative medicine
Transurethral resection of the prostate (TURP) is a common procedure for the treatment of benign prostatic hyperplasia (BPH). Previous studies on the effect of 5-alpha reductase inhibitors on perioperative blood loss in TURP and microvessel density (MVD) in the prostate are equivocal. We evaluated whether pretreatment with finasteride for 2 weeks before surgery can reduce perioperative blood loss in TURP and MVD in the prostate.