Open AccessIs preoperative neutrophil-to-lymphocyte ratio a red flag which can predict high-risk pathological characteristics in renal cell carcinoma?
Author(s) -
Rajesh Kumar Reddy Adapala,
Girish Prabhu,
K N Sanman,
Durga Rao Yalla,
Raviraj Shetty,
P Venugopal
Publication year - 2021
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/ua.ua_34_19
Subject(s) - medicine , pathological , renal sinus , nephrectomy , neutrophil to lymphocyte ratio , renal cell carcinoma , pathology , stage (stratigraphy) , flag (linear algebra) , lymphovascular invasion , lymphocyte , necrosis , cancer , kidney , biology , metastasis , paleontology , algebra over a field , mathematics , pure mathematics
Renal cell carcinoma (RCC) is known to invoke both immunological and inflammatory responses. While the neutrophils mediate the tumor-induced inflammatory response, the lymphocytes bring about the various immunological events associated with it. The neutrophil-to-lymphocyte ratio (NLR) is a simple indicator of this dual response. We investigated the association between preoperative NLR and histopathological prognostic variables of RCC intending to find out whether it can be of value as a red flag capable of alerting the clinician as to the biological character of the tumor under consideration.