Open AccessEffect of hormonal manipulation using clomiphene citrate prior to microdissection testicular sperm retrieval
Author(s) -
Khalid Alrabeeah,
Abdulmalik Addar,
Ali Alothman,
Saad Abu Melha,
Abdullah Alkhayal
Publication year - 2021
Publication title -
urology annals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.355
H-Index - 20
eISSN - 0974-7834
pISSN - 0974-7796
DOI - 10.4103/ua.ua_129_20
Subject(s) - sperm retrieval , testicular sperm extraction , medicine , microdissection , azoospermia , luteinizing hormone , testosterone (patch) , gynecology , hormone , sperm , urology , andrology , spermatogenesis , endocrinology , infertility , biology , pregnancy , biochemistry , genetics , gene
Microdissection Testicular Sperm Extraction (micro-TESE) is a surgical method used for retrieving sperm from men with non-obstructive azoospermia. Clomiphene citrate (CC) is a selective estrogen receptor modulator (SERM) that stimulates luteinizing hormone (LH) and follicle-stimulating hormone (FSH) production. It is believed that treating patients with CC prior to micro-TESE increases the chance of sperm retrieval.