Open AccessOptic nerve head plasmacytoma as a manifestation of multiple myeloma
Author(s) -
Kaitlin Sandor,
Jonathan A Micieli,
Jason H. Peragallo
Publication year - 2021
Publication title -
taiwan journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 9
eISSN - 2211-5072
pISSN - 2211-5056
DOI - 10.4103/tjo.tjo_81_20
Subject(s) - medicine , plasmacytoma , optic nerve , multiple myeloma , extramedullary plasmacytoma , orbit (dynamics) , presentation (obstetrics) , pathology , disease , radiology , anatomy , engineering , aerospace engineering
Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described.