Open AccessCentral retinal artery occlusion as the presenting manifestation of invasive rhino-orbital-cerebral mucormycosis
Author(s) -
Pritam Bawankar,
Sayalee Lahane,
Pooja Pathak,
Payal P. Gonde,
Anjali Singh
Publication year - 2020
Publication title -
taiwan journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 9
eISSN - 2211-5072
pISSN - 2211-5056
DOI - 10.4103/tjo.tjo_72_18
Subject(s) - medicine , mucormycosis , central retinal artery occlusion , rhizopus oryzae , occlusion , magnetic resonance imaging , retinal artery occlusion , ophthalmic artery , rare disease , rhizopus , central retinal artery , amphotericin b , surgery , retinal , radiology , disease , dermatology , pathology , ophthalmology , antifungal , blood flow , chemistry , food science , fermentation
Rhino-orbital-cerebral mucormycosis (ROCM) is a rare but devastating fungal infection caused by filamentous fungi of the family Mucoraceae. We report a rare case of unilateral ROCM in a diabetic patient where central retinal artery occlusion (CRAO) was the first manifestation of the disease. Magnetic resonance imaging scan revealed orbital and intracranial spread of the disease. Definitive diagnosis was established by culture of the biopsy specimen which showed Rhizopus oryzae on Sabouraud's dextrose agar. The patient was successfully treated with extensive debridement of sinuses and intravenous liposomal amphotericin B; however, the left eye remained blind following the CRAO.