Open AccessA case of adult-onset tubulointerstitial nephritis and uveitis syndrome presenting with granulomatous panuveitis
Author(s) -
Kemal Tekin,
Yasemin Özdamar Erol,
Olcay Kurtulan,
Dilek Ertoy Baydar
Publication year - 2020
Publication title -
taiwan journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 9
eISSN - 2211-5072
pISSN - 2211-5056
DOI - 10.4103/tjo.tjo_33_18
Subject(s) - medicine , uveitis , dermatology , nephritis , interstitial nephritis , pathology , ophthalmology , kidney
The tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disorder that is probably underdiagnosed in clinical practice. Ocular involvement in TINU syndrome not only presents with the nongranulomatous anterior uveitis in 80% of patients but also manifests as intermediate, posterior, or panuveitis. This case report mentions an adult male patient who presented with granulomatous iridocyclitis with panuveitis and mild renal insufficiency. Workup for connective tissue and infectious diseases was negative for the patient. He was diagnosed with TINU syndrome based on the findings of renal biopsy. Both the uveitis and nephritis promptly responded well to steroid treatment, and there was no recurrence during the follow-up of 24 months.