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Cutaneous polyarteritis nodosa treated with pentoxifylline and clobetasol propionate: A case report
Author(s) -
Nada Alquorain,
Abdullah S. Aljabr,
Nada Juman Alghamdi
Publication year - 2018
Publication title -
saudi journal of medicine and medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 2
eISSN - 1658-631X
pISSN - 2321-4856
DOI - 10.4103/sjmms.sjmms_148_16
Subject(s) - medicine , clobetasol propionate , dermis , dermatology , pentoxifylline , skin biopsy , polyarteritis nodosa , livedo reticularis , vasculitis , biopsy , disease , pathology , radiology , psoriasis
Cutaneous polyarteritis nodosa is a rare type of cutaneous vasculitis. It affects the small- and medium-sized arteries of the dermis and subcutaneous tissue without extracutaneous involvement. The diagnosis is by skin biopsy, and the characteristic finding is a leukocytoclastic vasculitis. We report a case of a 14-year-old Saudi girl who was referred to the dermatology service because of multiple ulceronecrotic lesions on the frontal aspects of the distal lower limbs. She had past medical consultations and treatment but without improvement. The histopathology confirmed the clinical diagnosis of cPAN, and ultimately, she responded to treatment with pentoxifylline and topical clobetasol propionate. It is important to be aware of this disease and refer the patient to the dermatology service for the appropriate evaluation and treatment.

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