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The 13 C-urea breath test ( 13 C-UBT) is preferred for non-invasive detection of Helicobacter pylori (H. pylori); however, its accuracy drops when results fall between 2‰ and 6‰ (called the gray zone). This study aimed to evaluate the accuracy of 13 C-UBT (cut-off point 4‰) between 2‰ and 6‰, find a more appropriate gray zone, and identify the factors influencing 13 C-UBT.

The necessity and appropriate range of the diagnostic “gray zone” of 13C-urea breath test