Open AccessA cross-sectional survey of multi-generation inflammatory bowel disease consanguinity and its relationship with disease onset
Author(s) -
Mahmoud Mosli,
Abdulelah Alzahrani,
Showlag Showlag,
Abdullah Alshehri,
Ahmed Saleh Hejazi,
Majed N. Alnefaie,
Adel Almaymuni,
Mubarak Abdullahi,
Mohammed Albeshir,
Eman Al-Sulais,
Hani Jawa,
Emad Aljahdli,
Salem M. Bazarah,
Yousef Qari
Publication year - 2017
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/sjg.sjg_125_17
Subject(s) - consanguinity , medicine , inflammatory bowel disease , ulcerative colitis , disease , gastroenterology , pediatrics
Background\Aim: Consanguinity influences the phenotypic variations of some hereditary and immune-mediated disorders, including inflammatory bowel disease. This study estimated the prevalence of consanguinity among the ancestors of patients with inflammatory bowel disease and examined the effect of various consanguinity levels on inflammatory bowel disease onset.