Open AccessReducing by 50% the incidence of maternal hypotension during elective caesarean delivery under spinal anesthesia: Effect of prophylactic ondansetron and/or continuous infusion of phenylephrine - a double-blind, randomized, placebo controlled trial
Author(s) -
J.R. Ortiz-Gómez,
F.J. Palacio-Abizanda,
F. Morillas-Ramírez,
Inocencia Fornet-Ruiz,
Ana Lorenzo-Jiménez,
Maria Lourdes Bermejo-Albares
Publication year - 2017
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/sja.sja_237_17
Subject(s) - medicine , anesthesia , randomized controlled trial , spinal anesthesia , ondansetron , phenylephrine , placebo , caesarean delivery , incidence (geometry) , double blind , caesarean section , pregnancy , surgery , vomiting , blood pressure , pathology , physics , optics , biology , genetics , alternative medicine
Prophylactic administrations of ondansetron or phenylephrine have been reported to provide a protective effect against hypotension in women undergoing cesarean delivery under spinal anesthesia (SA). The main hypothesis is that ondansetron improves the hemodynamic response, especially combined with phenylephrine infusion.