Open AccessEffect of extended infusion of meropenem and nebulized amikacin on Gram-negative multidrug-resistant ventilator-associated pneumonia
Author(s) -
Mona Ahmed Ammar,
Waleed Abdalla
Publication year - 2018
Publication title -
saudi journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.416
H-Index - 24
eISSN - 1658-354X
pISSN - 0975-3125
DOI - 10.4103/sja.sja_148_17
Subject(s) - amikacin , medicine , ventilator associated pneumonia , meropenem , intensive care unit , pneumonia , anesthesia , nephrotoxicity , incidence (geometry) , antibiotics , gastroenterology , surgery , toxicity , antibiotic resistance , microbiology and biotechnology , biology , physics , optics
Ventilator-associated pneumonia (VAP) due to multidrug-resistant organisms (MDROs) is associated with a significant mortality in the Intensive Care Unit (ICU). The aim of this study was to compare the efficacy and safety of extended infusion of meropenem and nebulized amikacin on VAP caused by Gram-negative MDRO versus intravenous (IV) meropenem and amikacin alone.