Open AccessAutonomic receptors and nitric-oxide involvements in mediating vasorelaxation effect induced by Syzygium polyanthum leaves extract
Author(s) -
Azlini Ismail,
Wan Amir Nizam Wan Ahmad
Publication year - 2017
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/pr.pr_69_17
Subject(s) - nitric oxide , myograph , pharmacology , muscarinic acetylcholine receptor , receptor , chemistry , atropine , propranolol , nitric oxide synthase , endocrinology , medicine
Syzygium polyanthum (Wight) Walp leaves are traditionally used by Malays for treating hypertension. Our previous study showed that aqueous extract of S. polyanthum (AESP) and methanolic extract of S. polyanthum (MESP) extracts of S. polyanthum leaves significantly reduced blood pressure of normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR).