Open AccessThe activity of immunoglobulin Y anti-Mycobacterium tuberculosis on proliferation and cytokine expression of rat peripheral blood mononuclear cells
Author(s) -
Sri Agus Sudjarwo,
Koerniasari Eraiko,
Giftania Wardani Sudjarwo,
Koerniasari
Publication year - 2017
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/pr.pr_66_17
Subject(s) - peripheral blood mononuclear cell , mycobacterium tuberculosis , antigen , tuberculosis , cytokine , immunology , antibody , biology , interferon gamma , microbiology and biotechnology , reverse transcription polymerase chain reaction , gene expression , medicine , gene , in vitro , biochemistry , pathology
It has long been known that chickens, like mammals, are capable of producing antigen-specific immunoglobulin Y (IgY), which functions similar to IgG. The present study was performed to investigate the activity of IgY anti- Mycobacterium tuberculosis on proliferation, interleukin (IL)-2, and interferon (IFN)-γ expression of rat peripheral blood mononuclear cells (PBMCs).