Open Access
In vitro antiproliferative effect of earthworm coelomic fluid of Eudrilus eugeniae, Eisenia foetida, and Perionyx excavatus on squamous cell carcinoma-9 cell line: A pilot study
Author(s) -
Dominic Augustine,
Roopa S Rao,
J. Anbu,
Kotamballi N. Chidambara Murthy
Publication year - 2017
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/pr.pr_52_17
Subject(s) - earthworm , ic50 , cell culture , in vitro , cell growth , chemistry , pharmacology , growth inhibition , biology , biochemistry , ecology , genetics
The earthworm coelomic fluid (ECF) has shown proven antiproliferative effect against breast, liver, gastrointestinal, and brain cancer, but it is least explored in oral cancer. The present in vitro study is an attempt to investigate the antiproliferative activity of ECF on oral cancer cell line squamous cell carcinoma (SCC)-9.