Open AccessAnnonacin exerts antitumor activity through induction of apoptosis and extracellular signal-regulated kinase inhibition
Author(s) -
Chee Voon Yap,
K S Subramaniam,
Sik Wey Khor,
Ivy Chung
Publication year - 2017
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/pr.pr_19_17
Subject(s) - apoptosis , propidium iodide , programmed cell death , viability assay , annexin , cell cycle , traditional medicine , cell growth , biology , medicine , biochemistry
Endometrial cancer (EC) is the most common gynecologic malignancy in developed countries. Annonacin, a natural pure compound extracted from the seeds of Annona muricata , is a potential alternative therapeutic agent to treat EC.