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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine that activates apoptosis through death receptors on the cell surface and is regarded as a potential anticancer agent. However, many cancer cells are resistant to TRAIL-induced apoptosis.

pharmacognosy magazine

Herbal medicines showing synergistic effects with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) against A549 TRAIL-resistant lung cancer cells: A screening study