Open AccessHerbal medicines showing synergistic effects with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) against A549 TRAIL-resistant lung cancer cells: A screening study
Author(s) -
Shuen Cheng Chiang,
Yeon-Jung Choi,
ShiEun Kang,
Miyong Yun,
Beom-Joon Lee
Publication year - 2018
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/pm.pm_270_17
Subject(s) - apoptosis , cytotoxic t cell , pharmacology , tumor necrosis factor alpha , cytotoxicity , a549 cell , traditional medicine , radix (gastropod) , lung cancer , medicine , cancer cell , cancer , chemistry , in vitro , immunology , biochemistry , biology , botany
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine that activates apoptosis through death receptors on the cell surface and is regarded as a potential anticancer agent. However, many cancer cells are resistant to TRAIL-induced apoptosis.