Open AccessThe effect of thymoquinone on nuclear factor kappa B levels and oxidative DNA damage on experimental diabetic rats
Author(s) -
Ayşe Usta,
Semiha Dede
Publication year - 2017
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/pm.pm_134_17
Subject(s) - thymoquinone , streptozotocin , nigella sativa , phytochemical , chemistry , pharmacology , oxidative stress , malondialdehyde , diabetes mellitus , traditional medicine , antioxidant , intraperitoneal injection , medicine , biochemistry , endocrinology
Thymoquinone (TQ), the basic bioactive phytochemical constituent of seed oil of Nigella sativa , is one of these herbal drugs known for antidiabetic effects. This study was carried out to assess the effects of the possible role of TQ on nuclear factor kappa B (NF-κB) and oxidative DNA damage levels in experimental diabetic rats.