Open AccessCorrelation of CD133 and Oct-4 expression with clinicopathological and demographic parameters in oral squamous cell carcinoma patients
Author(s) -
Alok R. Singh,
Anand Srivastava,
Salman Akhtar,
Mohammad Haris Siddiqui,
Pooja Singh,
Vijay Kumar
Publication year - 2018
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/njms.njms_60_17
Subject(s) - medicine , stage (stratigraphy) , immunohistochemistry , basal cell , indian subcontinent , cancer , pathology , oncology , cancer stem cell , oral cavity , stem cell , clinical significance , cell , biology , history , paleontology , ancient history , genetics , orthodontics
Squamous cell carcinoma of oral cavity is one of the most common cancers of Indian subcontinent with the 5-year survival rate of 50% despite the recent advances in the treatment. The aim of the present study was to study cancer stem cell markers CD133 and Oct-4 in oral squamous cell carcinoma (OSCC) patients and their correlation with clinicopathological variables.