Open AccessAntibiotic therapy for the prevention of osteoradionecrosis following tooth extraction in head-and-neck cancer patients postradiotherapy: An 11-year retrospective study
Author(s) -
LuizFelipe Palma,
Marcelo Marcucci,
CíntiaMaria Remondes,
Leandro Chambrone
Publication year - 2021
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/njms.njms_413_21
Subject(s) - medicine , osteoradionecrosis , head and neck cancer , retrospective cohort study , radiation therapy , perioperative , dentistry , antibiotics , surgery , microbiology and biotechnology , biology
One of the most important complications of radiotherapy (RT) for head-and-neck cancer (HNC) is osteoradionecrosis (ORN) of the jaws, which mostly arises from tooth extractions. The ORN treatment still represents a great challenge; therefore, the prevention is of paramount importance. Thus, the present study aimed to evaluate retrospectively a perioperative systemic antibiotic therapy protocol for the prevention of ORN following tooth extraction in head-and-neck patients post-3D conformal RT.