Open AccessEvidence-based effectiveness of herbal treatment modality for recurrent aphthous ulcers – A systematic review and meta-analysis
Author(s) -
Arvind Srivastava,
Shivakumar Gc,
Swarnasmita Pathak,
Ekta Ingle,
Anjali Kumari,
Sahana Shivakumar,
Navin Kumar,
Akhilesh Kumar Singh
Publication year - 2021
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/njms.njms_249_20
Subject(s) - medicine , meta analysis , medline , web of science , intervention (counseling) , randomized controlled trial , oral mucosa , dermatology , traditional medicine , surgery , pathology , psychiatry , political science , law
Recurrent Apthous Ulcers (RAU) has affected mankind through time immemorial. It is the most commonly prevalent oral mucosal lesion manifesting as painful ulcers involving non - keratinised oral mucosa. This review was done to assess herbal intervention in RAU patients for outcomes of ulcer size and pain intensity. Literature search of published articles in Medline, Scopus, Ovid and Journal of Web upto August 2020 were reviewed for the pre-described outcomes. Revman 5.4 software was used for study analysis. Total 9 articles were finally chosen for qualitative analysis. Meta analytic comparison demonstrated the ulcer reduction (CI = -2.22 to - 0.09; p <0.001) and pain intensity (CI = -4.60 to - 0.08; p <0.001) was reduced in the herbal group as compared to the controls. A definite evidence of herbal intervention was noted in alleviating RAU signs and symptoms.