Open AccessEvaluation of the effectiveness of n-acetylcysteine in the prevention of colistin-induced nephrotoxicity: A randomized controlled clinical trial
Author(s) -
Sedigheh Mosayebi,
Rasool Soltani,
Fatemeh Shafiee,
Samane Assarzadeh,
Atousa Hakamifard
Publication year - 2021
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/jrpp.jrpp_90_21
Subject(s) - medicine , colistin , nephrotoxicity , creatinine , blood urea nitrogen , acute kidney injury , randomized controlled trial , urine , renal function , acetylcysteine , lipocalin , urinary system , urology , gastroenterology , pharmacology , kidney , antibiotics , antioxidant , biochemistry , chemistry , microbiology and biotechnology , biology
The present study aimed to evaluate the effectiveness of N-Acetylcysteine (NAC), as an antioxidant, in preventing nephrotoxicity in patients receiving colistin.