Open AccessMelatonin supplementation may improve the outcome of patients with hemorrhagic stroke in the intensive care unit
Author(s) -
Mehrnoush Dianatkhah,
Atabak Najafi,
Mohammad Sharifzadeh,
Arezoo Ahmadi,
Hamidreza Sharifnia,
Mojtaba Mojtahedzadeh,
Farhad Najmeddin,
Azadeh Moghaddas
Publication year - 2017
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/jrpp.jrpp_17_49
Subject(s) - medicine , melatonin , mechanical ventilation , sedation , anesthesia , intensive care unit , sedative , ventilation (architecture) , weaning , isoflurane , stroke (engine) , mechanical engineering , engineering
Although mechanical ventilation is frequently a life-saving therapy, its use can result in unwanted side effects. It has been well documented that the choice of sedating agent may influence the duration of mechanical ventilation. Melatonin is a sedative and analgesic agent without any respiratory depressant effect which makes it an attractive adjuvant for sedation in the intubated patients. The aim of this study is to evaluate the effect of melatonin on the duration of mechanical ventilation in patients with hemorrhagic stroke.