Open AccessLevosulpiride-induced Movement Disorders
Author(s) -
Supriyo Choudhury,
Koustav Chatterjee,
Rasnik Singh,
Shantanu Shubham,
Santosh Trivedi,
Suparna Chatterjee,
Hrishikesh Kumar
Publication year - 2017
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/jpp.jpp_32_17
Subject(s) - dyskinesia , parkinsonism , medicine , movement disorders , rating scale , adverse effect , pediatrics , anesthesia , psychology , disease , developmental psychology , parkinson's disease
We reported a series of patients who presented with LSP-induced movement disorders specifically, dyskinetic movements. We have presented one case of LSP-induced parkinsonism and summarized ten cases of LSP-induced dyskinesia. The causality of the adverse drug reaction was assessed systematically using a validated rating system, and we extensively qualified the clinical presentation of each case of dyskinesia using a clinical rating scale. We described an unusual case of acute onset LSP-induced parkinsonism in a 56-year-aged female. The mean age of ten patients of LSP-induced dyskinesia was 65.3 years (standard deviation 10.4), and 25% of patients were female. They were consuming suspected medication for a median duration of 13 months (range 1-60 months). We noted LSP-induced dyskinesia was challenging to treat as its resolution is often incomplete even with adequate treatment.