
Risperidone-Induced Adverse Drug Reactions and Role of DRD2 (−141 C Ins/Del) and 5HTR2C (−759 C>T) Genetic Polymorphisms in Patients with Schizophrenia
Author(s) -
Charanraj Goud Alladi,
Anbarasan Mohan,
Deepak Gopal Shewade,
Ravi Philip Rajkumar,
Adithan Chandrasekaran,
Karthick Subramanian
Publication year - 2017
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/jpp.jpp_197_16
Subject(s) - risperidone , medicine , odds ratio , adverse effect , weight gain , schizophrenia (object oriented programming) , cyp2d6 , gastroenterology , pharmacogenetics , endocrinology , genotype , psychiatry , biology , genetics , body weight , gene , cytochrome p450 , metabolism
To determine the adverse drug reaction (ADR) profile of risperidone and their association with dopamine ( DRD2 - 141 C Ins/Del/rs1799732) and serotonin receptor ( 5HTR2C -759 C>T/rs3813929) gene polymorphisms in patients with schizophrenia.