Open AccessMechanism Underlying Linezolid-induced Thrombocytopenia in a Chronic Kidney Failure Mouse Model
Author(s) -
Nao Nishijo,
Yasuhiro Tsuji,
Kazuhisa Matsunaga,
Masahiko Kutsukake,
Fumiyasu Okazaki,
Shiro Fukumori,
Hidefumi Kasai,
Yoichi Hiraki,
Ippei Sakamaki,
Yoshihiro Yamamoto,
Yoshiharu Karube,
Hideto To
Publication year - 2017
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/jpp.jpp_167_16
Subject(s) - medicine , linezolid , platelet , bone marrow , hematocrit , renal function , white blood cell , kidney , pharmacology , endocrinology , vancomycin , biology , bacteria , genetics , staphylococcus aureus
To investigate the relationship between renal function and linezolid (LZD)-induced thrombocytopenia and elucidate the underlying mechanism using a chronic renal disease (CRD) mouse model.