Open AccessTelomerase in saliva: An assistant marker for oral squamous cell carcinoma
Author(s) -
Firoza Samadi,
Shaista Suhail,
Manjari Sonam,
Mohammad Kaleem Ahmad,
Shaleen Chandra,
Mohammad Saleem
Publication year - 2019
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_83_19
Subject(s) - telomerase , telomere , ribonucleoprotein , malignant transformation , saliva , cancer research , biology , microbiology and biotechnology , pathology , medicine , rna , dna , genetics , gene , biochemistry
Telomerase is a ribonucleoprotein complex responsible for de novo telomere synthesis and addition of telomeric repeats to existing telomeres. Telomerase activity is generally found to be absent in normal tissues. Telomerase is known to be induced upon malignant transformation of human cells.