Open AccessExpression of cluster differentiation-44 stem cell marker in grades of oral epithelial dysplasia: A preliminary study
Author(s) -
Sashi Kiran Sanapala Venkat Naga,
P Chandra Shekar,
Kiran Kumar Kattappagari,
K Lalith Prakash Chandra,
G. Sridhar Reddy,
Baddam Venkat Ramana Reddy
Publication year - 2019
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_308_18
Subject(s) - dysplasia , leukoplakia , epithelial dysplasia , oral submucous fibrosis , cd44 , pathology , oral lichen planus , medicine , cluster of differentiation , staining , incidence (geometry) , fibrosis , gastroenterology , cancer , biology , cell , genetics , physics , optics
Oral cancer is one among the alarming diseases related to oral cavity. Its prevalence and incidence have increased in many folds, in the past decade. This has led the investigators to find the preliminary stages and related early evaluating methods to restrain it. Few clinical lesions such as leukoplakia, erythroplakia, oral submucous fibrosis and lichen planus reflected malignant changes. These premalignant disorders provided scope to assess the underlying cellular and molecular events, which shall be helpful in early detection, aggressiveness and prognosis of the patient.