Open AccessAssessment of immunohistochemical expression of p16 in head and neck squamous cell carcinoma and their correlation with clinicopathological parameters
Author(s) -
Pinki Pandey,
Megha Ralli,
Aparna Banerjee Dixit,
Savita Agarwal,
V. N. Chaturvedi,
Anshul Sawhney,
Roopak Agarwal
Publication year - 2021
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_252_20
Subject(s) - immunohistochemistry , medicine , head and neck squamous cell carcinoma , oncology , basal cell , etiology , lymph node , pathology , head and neck cancer , cancer
Oral squamous cell carcinoma is a major cause of death throughout the developed world. It is associated with tobacco chewing, paan chewing and alcohol consumption. Human papillomavirus (HPV) type 16 has also been suggested to play a role in the etiology of head-and-neck squamous cell carcinoma (HNSCC). p16 expression is now being used as a surrogate marker of HPV infection in squamous cell carcinoma.