Open AccessNasopharyngeal carcinoma ex-pleomorphic adenoma (noninvasive): A report of a rare case
Author(s) -
Sujata Naik,
Purnima Das,
Rashmi Patnayak,
Santosh Kumar Swain
Publication year - 2021
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_241_20
Subject(s) - carcinoma ex pleomorphic adenoma , pleomorphic adenoma , pathology , medicine , histopathological examination , immunohistochemistry , adenoma , neoplasm , soft tissue , salivary gland
Pleomorphic adenoma (PA) is the most common type of benign tumors of minor salivary glands. A carcinoma ex-pleomorphic adenoma (CXPA) is a malignant epithelial neoplasm originating from either a primary or recurrent benign PA. The nasopharynx is an extremely uncommon location for this tumor. A 32-year-old male had complaints of nasal blockage. In noncontrast computed tomography, a soft-tissue mass was present in the nasopharynx. Histopathological and immunohistochemical examination of the endoscopically excised mass revealed features of CXPA, noninvasive in nature. Careful histopathological examination is the key to identify this uncommon entity. To the best of our knowledge, <20 cases have been published so far.