Open AccessA curious case of central odontogenic fibroma: A novel perspective
Author(s) -
Chetana Chandrashekar,
Subhalakshmi Sen,
Venkadasalapathi Narayanaswamy,
Raghu Radhakrishnan
Publication year - 2018
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_156_16
Subject(s) - mast (botany) , mast cell , odontogenic , pathogenesis , biology , stem cell factor , chymase , pathology , stem cell , microbiology and biotechnology , medicine , immunology , haematopoiesis
We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described.