Open AccessMyofibroblasts: Master of disguise
Author(s) -
Bhavana S Bagalad,
Kirthi Kumar,
H K Puneeth
Publication year - 2017
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_146_15
Subject(s) - myofibroblast , inflammation , regeneration (biology) , microbiology and biotechnology , carcinogenesis , population , organogenesis , biology , pathology , secretion , medicine , immunology , cancer , fibrosis , endocrinology , genetics , environmental health , gene
Myofibroblasts are the unique population of smooth muscle-like fibroblasts. These cells have a role in growth factors secretion, matrix deposition and degradation. Thereby, myofibroblast contributes in both human physiology and pathology. This review explains the myofibroblastic lesions, imperative role of myofibroblasts in organogenesis, repair, regeneration, inflammation and tumorigenesis.