Open AccessAnticancer and antiproliferative efficacy of a standardized extract of Vaccinium macrocarpon on the highly differentiating oral cancer KB cell line athwart the cytotoxicity evaluation of the same on the normal fibroblast L929 cell line
Author(s) -
Anil V Ankola,
Vaibhav Kumar,
Simran Thakur,
Richa Singhal,
T Smitha,
Roopali Sankeshwari
Publication year - 2020
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/jomfp.jomfp_129_20
Subject(s) - cytotoxicity , mtt assay , cell culture , maceration (sewage) , fibroblast , pharmacology , traditional medicine , chemistry , cell , in vitro , medicine , biology , biochemistry , genetics , materials science , composite material
The perpetual search is on to find botanical complementary adjuncts to the conventional therapies used that is not only cost-effective but also reduces side effects associated with conventional synthetic drugs that are available in the market. The aim of this study was to assess the in vitro anticancer efficacy of hydroalcoholic fruit extract of cranberry against oral cancer KB cell line by Di-Methyl Thiazoldiphenyl Tetrazolium bromide assay (MTT) assay and its cytotoxicity on normal fibroblast cells.