Open AccessPropofol sparing effect of dexmedetomidine and magnesium sulfate during BIS targeted anesthesia: A prospective, randomized, placebo controlled trial
Author(s) -
Chiteshwar Walia,
Rajesh Gupta,
Manjot Kaur,
Lakshmi Mahajan,
Gaganjot Kaur,
Bhanupreet Kaur
Publication year - 2018
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/joacp.joacp_297_17
Subject(s) - dexmedetomidine , medicine , propofol , anesthesia , anesthetic , saline , loading dose , hemodynamics , sedation , placebo , magnesium , randomized controlled trial , surgery , pathology , materials science , metallurgy , alternative medicine
Maintenance of adequate depth of anesthetic is crucial to prevent awareness and to reduce stress response associated with surgery. Goals of balanced general anesthetic are met by use of adjuvants to facilitate use of lower anesthetic dose, while ensuring adequate anesthetic depth. This study employed BIS monitoring to compare the anesthetic sparing effects of intravenous dexmedetomidine and magnesium sulphate on induction dose of propofol by maintaining a BIS value of 40-50.