Open AccessAssessment of single- and double-strand breaks in DNA induced by auger electrons of radioisotopes used in diagnostic and therapeutic applications
Author(s) -
Mahdi Seifi Moradi,
Babak Shirani Bidabadi
Publication year - 2020
Publication title -
journal of medical physics/journal of medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 24
eISSN - 1998-3913
pISSN - 0971-6203
DOI - 10.4103/jmp.jmp_79_19
Subject(s) - auger effect , dna , auger , electron , auger electron spectroscopy , molecule , radiochemistry , double strand , chemistry , atomic physics , dna damage , physics , nuclear physics , biochemistry , organic chemistry
Most of the radionuclides that are used for diagnostic purposes emit Auger electrons and can thus cause damage to the DNA molecule on a nanometer scale. Therefore, the nanodosimetric calculation of these radioisotopes is necessary to achieve better understanding on their effects.