Open AccessPediatric craniospinal irradiation – The implementation and use of normal tissue complication probability in comparing photon versus proton planning
Author(s) -
M.K. Shobana,
S Balasubramanian
Publication year - 2021
Publication title -
journal of medical physics/journal of medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 24
eISSN - 1998-3913
pISSN - 0971-6203
DOI - 10.4103/jmp.jmp_75_21
Subject(s) - tomotherapy , medicine , proton therapy , radiation treatment planning , radiation therapy , medulloblastoma , nuclear medicine , complication , dosimetry , radiology , surgery , pathology
The preferred radiotherapy treatment for medulloblastoma is craniospinal irradiation (CSI). With the aim of developing the potential to reduce normal tissue dose and associated post-treatment complications with photon and proton radiotherapy techniques for CSI. This report aims to carefully compare and rank treatment planning and dosimetric outcomes for pediatric medulloblastoma patients using normal tissue complication probability (NTCP) formalism between photon (three-dimensional conformal radiotherapy, intensity-modulated radiotherapy [IMRT], volumetric-modulated arc therapy [VMAT], and HT) and proton CSI.