Open AccessEstablishment of a new three-dimensional dose evaluation method considering variable relative biological effectiveness and dose fractionation in proton therapy combined with high-dose-rate brachytherapy
Author(s) -
Daisuke Kobayashi,
Takeshi Isobe,
Kunio Takada,
Yoki Mori,
Hiroyuki Takei,
Hiroaki Kumada,
Satoshi Kamizawa,
Takahiro Tomita,
Eisuke Sato,
Harumasa Yokota,
Takeji Sakae
Publication year - 2019
Publication title -
journal of medical physics/journal of medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 24
eISSN - 1998-3913
pISSN - 0971-6203
DOI - 10.4103/jmp.jmp_117_18
Subject(s) - sobp , relative biological effectiveness , proton therapy , nuclear medicine , brachytherapy , effective dose (radiation) , proton , fractionation , dose fractionation , dosimetry , radiation therapy , medicine , radiation , chemistry , physics , radiology , nuclear physics , organic chemistry
The purpose of this study is to evaluate the influence of variable relative biological effectiveness (RBE) of proton beam and dose fractionation has on dose distribution and to establish a new three-dimensional dose evaluation method for proton therapy combined with high-dose-rate (HDR) brachytherapy.