Open AccessInositols in Midlife
Author(s) -
Sanjay Kalra,
Bharti Kalra
Publication year - 2018
Publication title -
journal of mid-life health
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 11
eISSN - 0976-7819
pISSN - 0976-7800
DOI - 10.4103/jmh.jmh_52_16
Subject(s) - inositol , animal studies , clinical trial , medicine , gerontology , pharmacology , physiology , endocrinology , receptor
This review describes the mechanistic, animal, and clinical data related to the use of inositols in midlife. It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol and randomized controlled trials conducted in postmenopausal women with metabolic syndrome and supports these data with the results of in vitro and animal studies on inositol in nephropathy and other related conditions. Recent advances related to biochemistry, pharmaceutical science, and genetics are discussed. It concludes that inositols have a potential role to play in maintaining metabolic health in postmenopausal women.