Open AccessChemopreventive agents in oral premalignancy: A medical management review
Author(s) -
Chintada Suvarna,
Nallan Csk Chaitanya,
Shaik Ameer,
Pavitra Inamdar,
Swetha Alugubelli,
Alakananda Bhagyanagar
Publication year - 2020
Publication title -
journal of international society of preventive and community dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 14
eISSN - 2250-1002
pISSN - 2231-0762
DOI - 10.4103/jispcd.jispcd_424_19
Subject(s) - medicine , malignancy , medline , cochrane library , medical literature , carcinogenesis , intensive care medicine , cancer , oncology , bioinformatics , alternative medicine , pathology , political science , law , biology
The term chemoprevention denotes the use of specific natural or synthetic chemical agents to prevent carcinogenesis. Chemoprevention may help delay the process of carcinogen activation and prevent the conversion of preneoplastic cells. These agents play an active role in the secondary level of prevention and reduce malignancy-associated morbidity and mortality. A new term, "prophylactic antioxidant therapy," was coined and proposed. This review has assessed all major chemopreventive agents used for oral premalignancy and malignant conditions, which will reduce the economic burden on the patients.