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The efficacy of carbon dioxide (CO 2 ) laser irradiation combined with fluoride in inhibiting enamel demineralization has been demonstrated by several laboratory investigations. However, there are very few reports about the in situ or in vivo caries preventive effect of CO 2 laser combined with topical fluoride on dental enamel. Hence, an in situ study was designed and carried out to assess inhibition of mineral loss from human tooth enamel by CO 2 laser and 1.23% acidulated phosphate fluoride (APF).

Assessment of inhibition of mineral loss from human tooth enamel by carbon dioxide laser and 1.23% acidulated phosphate fluoride