Open AccessLeprosy-associated chronic wound management using biomaterials
Author(s) -
Sivasubramanian Srinivasan,
Mohana Sambasivam,
Paulraj Maheswari,
Victor Victoria,
Ramar Thangam,
Jayashri Mahalingam,
Gayathri Chandrasekar-Janebjer,
Vincent Savariar,
Balaraman Madhan,
Palani Gunasekaran,
Satish Srinivas Kitambi
Publication year - 2018
Publication title -
journal of global infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 25
eISSN - 0974-8245
pISSN - 0974-777X
DOI - 10.4103/jgid.jgid_79_17
Subject(s) - leprosy , medicine , dermatology
Deformities and neuropathic chronic ulcers are the common features associated with leprosy-cured individuals that impact their quality of life and impair rehabilitation efforts. The challenging aspects for treatment of chronic wounds are the factors that inhibit healing. We reasoned that limited success of various therapeutic interventions could be due to the fact that leprosy-cured individual's physiology gets acclimatized to having a chronic wound that any therapeutic intervention is counterbalanced to maintain status quo at the wound site. Therefore, an alternative strategy would be to use biomaterials that gradually alter the wound site allowing the individual's physiology to participate in the healing process.