Open AccessTherapeutic properties of botulinum toxin on chronic anal fissure treatment and the patient factors role
Author(s) -
Setareh Soltany,
Hamid Hemmati,
Jafar Alavy Toussy,
Dina Salehi,
Parisa Alavi Toosi
Publication year - 2020
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_944_19
Subject(s) - medicine , anal fissure , botulinum toxin , surgery , anesthesia , pathogenesis
One of the most frequent distressing diseases which causes anal pain and bleeding after defecation is anal fissure. Despite a poorly understood pathogenesis, the internal anal sphincter spasm has been identified to play a central role in pathogenesis. Recently, botulinum toxin is being used increasingly for the treatment of chronic anal fissure to achieve chemical sphincterotomy and reduce internal sphincter tonicity. Based on the heterogeneity among the published studies, we aimed this study to evaluate its healing rate and for recognizing the factors of patients which may affect the outcome.