Open AccessStudy of the prevalence of Multidrug-Resistant Pulmonary Tuberculosis (MDR-TB) in Western Rajasthan using line probe assay
Author(s) -
Mukesh Sharma,
Deepak Kumar,
Gopal Krishna Bohra,
Durga Shankar Meena,
Sunil Kumar Bhambu
Publication year - 2020
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_916_19
Subject(s) - medicine , sputum , rifampicin , isoniazid , mycobacterium tuberculosis , tuberculosis , drug resistance , multiple drug resistance , sputum culture , microbiology and biotechnology , multiplex , pathology , biology , bioinformatics
To determine the prevalence of MDR-TB and find out the incidence of drug resistance using molecular diagnostic method. Line probe assay (LPA) is based on the principle of multiplex PCR is used to detect MTB ( Mycobacterium tuberculosis ) complex as well as its sensitivity to rifampicin and isoniazid.