Open AccessSeizure associated with olanzapine
Author(s) -
N A Uvais,
Vanteemar S. Sreeraj
Publication year - 2018
Publication title -
journal of family medicine and primary care
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_405_16
Subject(s) - olanzapine , medicine , seizure disorders , seizure threshold , schizophrenia (object oriented programming) , psychiatry , pediatrics , epilepsy , anesthesia , anticonvulsant
Atypical antipsychotics are known to be associated with electroencephalogram abnormalities. Olanzapine can lower seizure threshold and induce epileptiform discharges. However in patients on Olanzapine for the treatment of a primary psychiatric disorder, clinical seizure is a rare occurrence. We report the case of a 23-year-old female with mild mental retardation with schizophrenia with obsessive compulsive disorder who developed new-onset generalized tonic-clonic seizure probably due to Olanzapine. Electroencephalogram showed epileptiform discharges. The seizure risk associated with Olanzapine was reviewed.