Open AccessSimultaneous detection of IgM antibodies against dengue and chikungunya: Coinfection or cross-reactivity?
Author(s) -
Kumar S Abhishek,
Anita Chakravarti
Publication year - 2019
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_365_19
Subject(s) - chikungunya , dengue fever , coinfection , medicine , serology , outbreak , virology , population , immunology , antibody , virus , environmental health
Dengue and chikungunya sharing same mosquito vector are two most important arboviruses circulating in northern India including Delhi and are responsible for frequent outbreaks. Antigen and antibodies detection ELISA kits are the major tool to diagnose these viral illnesses, and are sometimes associated with cross-reactivity, giving a false picture of coinfection, although simultaneous harboring of both the viruses is not uncommon. Various studies have reported coinfection up to 25% from the same region.